KMID : 0614620100550030194
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Korean Journal of Gastroenterology 2010 Volume.55 No. 3 p.194 ~ p.197
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A Case of Non-occulsive Mesentery Ischemia with Pulmonary Embolism due to Protein C Deficiency
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Kim Tae-Wan
Choi Sung-Youn Kang Im-Ju Kang Yoon-Jung Shin Dong-Hyuk
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Abstract
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Protein C is an important physiological anticoagulant factor. Protein C deficiency has been linked to venous thrombosis at unusual sites, including the cerebral and mesenteric veins. Hereditary protein C deficiency is inherited primarily as an autosomal dominant trait with incomplete penetrance. Protein C and S deficiencies are known to increase the risk of venous thrombosis and pulmonary thromboembolism. Testing for protein C levels and function is necessary for the detection of both type I and type II protein C deficiency. In this article, we report a case of pulmonary embolism and mesentery ischemia due to type 1 protein C deficiency.
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KEYWORD
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Protein C deficiency, Ischemia, Mesentery, Pulmonary embolism
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